diff --git a/pkgs/applications/networking/browsers/firefox/common.nix b/pkgs/applications/networking/browsers/firefox/common.nix
index 9321e491099..25eb34c95e8 100644
--- a/pkgs/applications/networking/browsers/firefox/common.nix
+++ b/pkgs/applications/networking/browsers/firefox/common.nix
@@ -23,6 +23,7 @@
 # build time
 , autoconf
 , cargo
+, dump_syms
 , makeWrapper
 , nodejs
 , perl
@@ -168,6 +169,11 @@ buildStdenv.mkDerivation ({
 
   inherit src unpackPhase meta;
 
+  outputs = [
+    "out"
+    "symbols"
+  ];
+
   # Add another configure-build-profiling run before the final configure phase if we build with pgo
   preConfigurePhases = lib.optionals pgoSupport [
     "configurePhase"
@@ -196,6 +202,7 @@ buildStdenv.mkDerivation ({
   nativeBuildInputs = [
     autoconf
     cargo
+    dump_syms
     llvmPackages.llvm # llvm-objdump
     makeWrapper
     nodejs
@@ -231,13 +238,17 @@ buildStdenv.mkDerivation ({
     # Set consistent remoting name to ensure wmclass matches with desktop file
     export MOZ_APP_REMOTINGNAME="${binaryName}"
 
-    # Use our own python
-    export MACH_USE_SYSTEM_PYTHON=1
-
     # AS=as in the environment causes build failure
     # https://bugzilla.mozilla.org/show_bug.cgi?id=1497286
     unset AS
 
+  '' + lib.optionalString (lib.versionAtLeast version "100.0") ''
+    # Use our own python
+    export MACH_BUILD_PYTHON_NATIVE_PACKAGE_SOURCE=system
+  '' + lib.optionalString (lib.versionOlder version "100.0") ''
+    # Use our own python
+    export MACH_USE_SYSTEM_PYTHON=1
+
   '' + lib.optionalString (lib.versionAtLeast version "95.0") ''
     # RBox WASM Sandboxing
     export WASM_CC=${pkgsCross.wasi32.stdenv.cc}/bin/${pkgsCross.wasi32.stdenv.cc.targetPrefix}cc
@@ -408,7 +419,13 @@ buildStdenv.mkDerivation ({
   # tests were disabled in configureFlags
   doCheck = false;
 
+  # Generate build symbols once after the final build
+  # https://firefox-source-docs.mozilla.org/crash-reporting/uploading_symbol.html
   preInstall = ''
+    ./mach buildsymbols
+    mkdir -p $symbols/
+    cp mozobj/dist/*.crashreporter-symbols.zip $symbols/
+
     cd mozobj
   '';
 
diff --git a/pkgs/development/tools/dump_syms/default.nix b/pkgs/development/tools/dump_syms/default.nix
new file mode 100644
index 00000000000..a8c6821f27f
--- /dev/null
+++ b/pkgs/development/tools/dump_syms/default.nix
@@ -0,0 +1,46 @@
+{ lib
+, rustPlatform
+, fetchFromGitHub
+, pkg-config
+, openssl
+}:
+
+let
+  pname = "dump_syms";
+  version = "unstable-2022-05-05";
+in
+rustPlatform.buildRustPackage {
+  inherit pname version;
+
+  src = fetchFromGitHub {
+    owner = "mozilla";
+    repo = pname;
+    rev = "c2743d59b5aa321ade698f84b90f86b3d35a1b06";
+    hash = "sha256-hWK9KrYqbfrF8b7i33InlTa/XkoZs+h49kUsKeSaAok=";
+  };
+
+  cargoSha256 = "sha256:0vsr867nl156wpxpw01bv9fxsp6rhj9vvpz2i2yhx4kjgr1qk1kw";
+
+  nativeBuildInputs = [
+    pkg-config
+  ];
+
+  buildInputs = [
+    openssl
+  ];
+
+  checkFlags = [
+    # Disable tests that require network access
+    # ConnectError("dns error", Custom { kind: Uncategorized, error: "failed to lookup address information: Temporary failure in name resolution" })) }', src/windows/pdb.rs:725:56
+    "--skip windows::pdb::tests::test_ntdll"
+    "--skip windows::pdb::tests::test_oleaut32"
+  ];
+
+  meta = with lib; {
+    changelog = "https://github.com/mozilla/dump_syms/releases/tag/v${version}";
+    description = "Command-line utility for parsing the debugging information the compiler provides in ELF or stand-alone PDB files";
+    license = licenses.asl20;
+    homepage = "https://github.com/mozilla/dump_syms/";
+    maintainers = with maintainers; [ hexa ];
+  };
+}
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index c3226537e8b..eb1ed2c4b0d 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -5313,6 +5313,8 @@ with pkgs;
     autoreconfHook = buildPackages.autoreconfHook269;
   };
 
+  dump_syms = callPackage ../development/tools/dump_syms { };
+
   dumptorrent = callPackage ../tools/misc/dumptorrent { };
 
   duo-unix = callPackage ../tools/security/duo-unix { };