diff --git a/pkgs/development/python-modules/flask-restful/default.nix b/pkgs/development/python-modules/flask-restful/default.nix
index 25f02b87c9e..cefedfe7fc3 100644
--- a/pkgs/development/python-modules/flask-restful/default.nix
+++ b/pkgs/development/python-modules/flask-restful/default.nix
@@ -10,6 +10,7 @@
 , pythonOlder
 , pytz
 , six
+, werkzeug
 }:
 
 buildPythonPackage rec {
@@ -25,7 +26,7 @@ buildPythonPackage rec {
     hash = "sha256-zOxlC4NdSBkhOMhTKa4Dc15s7VjpstnCFG1shMBvpT4=";
   };
 
-  patches = [
+  patches = lib.optionals (lib.versionAtLeast werkzeug.version "2.1.0") [
     ./werkzeug-2.1.0-compat.patch
   ];