diff --git a/pkgs/development/libraries/grpc/default.nix b/pkgs/development/libraries/grpc/default.nix
index f55e2c2f6e4..d7576594adc 100644
--- a/pkgs/development/libraries/grpc/default.nix
+++ b/pkgs/development/libraries/grpc/default.nix
@@ -20,7 +20,7 @@
 
 stdenv.mkDerivation rec {
   pname = "grpc";
-  version = "1.45.2"; # N.B: if you change this, please update:
+  version = "1.46.1"; # N.B: if you change this, please update:
     # pythonPackages.grpcio-tools
     # pythonPackages.grpcio-status
 
@@ -28,7 +28,7 @@ stdenv.mkDerivation rec {
     owner = "grpc";
     repo = "grpc";
     rev = "v${version}";
-    sha256 = "sha256-l2r1NdbfwViXfLcwbfUgLueqfAVnLzI+gdEarlkIqkI=";
+    sha256 = "sha256-jci45jCcm2EN+tw7KCU9tOVB0jIADitQWoUlvyutRqw=";
     fetchSubmodules = true;
   };
 
diff --git a/pkgs/development/python-modules/grpcio-status/default.nix b/pkgs/development/python-modules/grpcio-status/default.nix
index 173353fc9f2..4e72e19392f 100644
--- a/pkgs/development/python-modules/grpcio-status/default.nix
+++ b/pkgs/development/python-modules/grpcio-status/default.nix
@@ -9,14 +9,14 @@
 
 buildPythonPackage rec {
   pname = "grpcio-status";
-  version = "1.45.0";
+  version = "1.46.1";
   format = "setuptools";
 
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-S6rY6Ow8RHiOA4wk49fccCWeBroJ9ApbgXhThWO6Plo=";
+    sha256 = "700ad7bdc2da6b1d873ae9abffd957b3df6b74c8ca4b34c50bf1b062ae10a620";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/grpcio-tools/default.nix b/pkgs/development/python-modules/grpcio-tools/default.nix
index b3794e8b9d4..b8bc4c9b540 100644
--- a/pkgs/development/python-modules/grpcio-tools/default.nix
+++ b/pkgs/development/python-modules/grpcio-tools/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "grpcio-tools";
-  version = "1.45.0";
+  version = "1.46.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-oBbPwh4NkbOwNtPU+WjR/eqGXfoDUkyx++yoRxn9RaI=";
+    sha256 = "d54d80a4cfd7da002893711af613c9c9358dddfdd27feea44eb902c495b09105";
   };
 
   outputs = [ "out" "dev" ];
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index d216c9ac669..9d0f42e685f 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -17568,7 +17568,7 @@ with pkgs;
 
   grpc = callPackage ../development/libraries/grpc {
     # grpc builds with c++14 so abseil must also be built that way
-    abseil-cpp = abseil-cpp.override {
+    abseil-cpp = abseil-cpp_202111.override {
       cxxStandard = "14";
     };
   };