diff --git a/pkgs/applications/science/biology/freebayes/default.nix b/pkgs/applications/science/biology/freebayes/default.nix
index 8646b8ca54a..5c2f09a4fae 100644
--- a/pkgs/applications/science/biology/freebayes/default.nix
+++ b/pkgs/applications/science/biology/freebayes/default.nix
@@ -15,6 +15,12 @@ stdenv.mkDerivation rec {
 
   buildInputs = [ zlib bzip2 xz ];
 
+  # Workaround build failure on -fno-common toolchains like upstream
+  # gcc-10. Otherwise build fails as:
+  #   ld: foomatic_rip-options.o:/build/foomatic-filters-4.0.17/options.c:49: multiple definition of `cupsfilter';
+  #     foomatic_rip-foomaticrip.o:/build/foomatic-filters-4.0.17/foomaticrip.c:158: first defined here
+  NIX_CFLAGS_COMPILE = "-fcommon";
+
   installPhase = ''
     install -vD bin/freebayes bin/bamleftalign scripts/* -t $out/bin
   '';